François-Marie Bissot de Vinsenne (17 June 1700 – 25 March 1736) was the son of Jean-Baptiste Bissot de Vinsenne and had a career with the colonial troops of Canada and was a half pay officer with the troops of Louisiana.
At an early age Bissot accompanied his father to the Maumee River area in present day northeastern Indiana where his father was in charge of promoting loyalty to the French among the Miami Indians. By 1718 he was working among the Ouyatanon Miamis on the upper [[Wabash River|Ouabache River. Four years later, he was commandant of that post.
In the ensuing years, the area became increrasingly important to New France in keeping their connection to Louisiana open and keeping British traders out. Vinsenne was central to this endeavour and also became increasingly attached to the Louisiana contingent. As part of the efforts to consolidate the area he brought in French settlers and founded a colony which became Vincennes, Indiana.
In 1736, François-Marie Bissot de Vinsenne was burned by the Chickasaws along with many other captive French near the present site of Fulton, Mississippi. This was the result of ill advised raids in coordination with Pierre D'Artaguiette. The raids are now known as the Campaign of 1736 of the Chickasaw Wars.